Lotus Weight Loss - CQC regulated clinic CQC regulated clinic | Enjoy £20 off with codeDOUBLE10

⚠️ Ordering Limits (from 1st Sept)

✅ You can only order from Lotus if you’ve had 2 pens or less in the last 28 days.

🚫 If you’ve already had 3 or more pens in the last 28 days, your order will be cancelled & refunded.

Please note: Due to high demand, orders may take up to 1-2 days to process.
Follow us on Instagram for updates.

GLP-1 Maintenance

Clinically safe guidance for keeping your weight loss results from GLP-1

You’ve put in serious work. Now let’s protect your results. Together we’ll decide whether to continue, reduce, taper or stop. We’ll also give you a simple plan you can actually follow.

Mounjaro (Tirzepatide) maintenance advice

Mounjaro (Tirzepatide) maintenance advice

Keep your results on the lowest effective weekly dose.

  • Comfortable and steady? Hold your dose and review every 8-12 weeks.
  • Hunger or 2-3 kg gain in 4-8 weeks? Step up one tier and book a review.
  • On the pill? Starting or stepping-up, add non-oral contraception for 4 weeks.

Read full advice

Wegovy (Semaglutide) maintenance advice

Wegovy (Semaglutide) maintenance advice

Most people can maintain on 1.7mg or 2.4mg weekly.

  • Settled but side-effects? Try stepping down from 2.4mg to 1.7mg and monitor.
  • Appetite back or weight creeping? Step back up and review in 4-8 weeks.
  • Planning pregnancy? Stop dose less than 2 months before trying to conceive.

Read full advice

Ozempic (Semaglutide) maintenance advice

Ozempic (Semaglutide) maintenance advice

Ozempic is Semaglutide licensed for type 2 diabetes.

  • Weight loss can happen, but dosing and goals differ from Wegovy.
  • Our guide explains the differences, safe options, and when a licensed weight management dose may be more appropriate.
  • Guide coming soon.

Coming soon

Clinician message

When to contact us urgently

  • Suspected or confirmed pregnancy while still on treatment.
  • Persistent vomiting / dehydration or inability to keep fluids down.
  • Severe abdominal pain, especially with fever or vomiting.
  • Fainting, marked weakness, or genuine signs of malnutrition.
  • Any eating-disorder concerns or rapid, unexpected weight loss

Patient testimonials

What patients say about Lotus

Patients of Lotus weight loss consistently rate us 5 stars. Here’s what some of those patients have to say.

Your options at goal (choose what fits right now)

No one‑size‑fits‑all. We’ll pick the route that feels sustainable, and change it later if life changes.

Your options

  • Continue: Hold your current dose if weight, appetite and side‑effects are steady.
  • Reduce: Step down to a lower dose to see if you stay steady with less medication.
  • Taper: A slow, supported glide to zero with a clear safety net if hunger creeps back.
  • Stop: Stop and follow a simple check‑in plan; fast access back to care if you need it.
How do I pick which option?

We look at your goals, dose tolerance, appetite, side‑effects and plans (e.g., pregnancy). We choose the least medication that keeps you well.

Absolutely. We review at 8-12 weeks and can switch paths.

Yes. We move one step at a time and set a safety net (when to step back up and how to contact us).

GLP-1 maintenance dosing at a glance

We aim for the lowest effective dose that keeps weight and appetite steady. That’s kinder on your body and your wallet. (We’ll consult with you to personalised your dose)

Dosing table (guide only)

TreatmentTypical maintenance rangeStep‑down examplesReview cadence
Semaglutide (Wegovy)1.7 or 2.4mg once weekly2.4 → 1.7mgReview every 8-12 weeks
Tirzepatide (Mounjaro / Zepbound)5, 10 or 15mg once weekly (can be higher)15 → 10mg or 10 → 5mgReview every 8-12 weeks
We can prescribe any licensed dose that works for you
Is 2.4 mg always ‘best’ for Wegovy?

No. ‘Best’ is the lowest dose that keeps you stable. Many maintain well on 1.7mg, but that isn’t always the case. Our clinicians can prescribe whatever maintenance dose works best for you.

We pick the nearest tier and let the review data guide the next step.

There’s no fixed rule in private care; NHS commissioning for Wegovy is up to 2 years in specialist services. We’ll personalise your plan.

What the evidence says

  • People who continue GLP‑1 maintenance lose more weight than those who stop.
  • Stopping often leads to some regain over time. How much varies by person.
  • A gradual taper can work for some, but medical evidence on this is mixed.

Clinic note: There isn’t a single ‘right’ answer here. We’ll agree a plan, check‑in at 8-12 weeks and adjust. If we taper, we’ll add extra monitoring and lifestyle support.

If I stop, will I regain weight?

Not always, but regain is common among patients who do not seek ongoing weight loss support along in conjunctions with your medication. That’s why we agree a safety net and act early if needed.

Current data supports ongoing use when tolerated well, with routine monitoring as an extra precaution.

Some people prefer the least medication possible; tapering tests whether that works for you.

Pregnancy & contraception safety

These are non‑negotiable for GLP-1 maintenance safety and simple once you know them.

  • Trying for a baby soon? Stop Semaglutide (Wegovy) at least 2 months before trying to conceive. Stop Tirzepatide (Mounjaro / Zepbound) at least 1 month before trying.
  • On the pill and Tirzepatide? Around starting or every dose increase, it can reduce how well oral contraception works. Use a non‑oral method for 4 weeks after starting .
  • Positive test while on treatment? Stop the medication and contact us promptly to discuss next steps.
Can I stay on GLP-1 until I get a positive test?

Please don’t. Plan to stop your treatment before trying (2 months for Semaglutide; 1 month for Tirzepatide).

Use a non‑oral method or add condoms for 4 weeks after starting and after each escalation.

This is not recommended in any capacity. Book a consultation with us so we can talk it through.

If weight creeps up (your regain trigger)

Small day‑to‑day changes are normal. We act when there’s a pattern.

Our trigger for action:

  • Weight up 2-3 kg in 4-8 weeks, or
  • Waistline increases 3 cm, or
  • Hunger & food noise noticeably back.

What to do:

  • Medication: Step up a single dose tier and book a 4-8 week review.
  • Lifestyle reset: Better sleep, reduce stress, protein at each meal. Consider simple resistance training.
  • Book a review: A short appointment now prevents drift.
What if it’s just water weight?

Focus on the 4-8 week trend, not a single day. If you’re unsure, book a short review.

Many feel appetite improve within 1-2 weeks of stepping up the dose. We’ll also reassess at 4-8 weeks.

Usually no. One tier up is enough unless there’s been a long break or tricky side‑effects.

Supporting your transition

Need personalised advice? Our clinicians are here to help

Use our live chat, contact form or email us at support@lotusweightloss.co.uk and we’ll support you every step of the way.

Get in touch today

Practical everyday concerns

Missed dose

  • Wegovy (Semaglutide): less than 5 days since your scheduled day? Take it now. More than 5 days, skip and take the next dose on your usual day. Don’t double up.
  • Tirzepatide (Mounjaro): if it’s less than 4 days (96 hours) since your scheduled day, take it now; if more than 4 days, skip and take the next dose on your usual day. Don’t double up.

Travel & time zones

  • Keep your pens refrigerated until use. Double-check out‑of‑fridge time limits. Mounjaro is typically 21 days if kept below 30 °C. Wegovy 28 days if kept between 8-30 °C.
  • For long‑haul trips, keep the 7‑day interval and adjust the clock time gradually.
  • Pack spares, needles and a small cool bag. Carry your medication in hand luggage.

Alcohol & big meals

  • Alcohol can worsen nausea and loosen food choices. If you drink, keep it light and eat slowly.
  • Very large or high‑fat meals can raise the chance of stomach upset. Eating smaller portions help.

Clinic note: If you’ve missed 2 weeks or more it’s important you contact us before restarting as you may need to step down and re‑titrate.

Common questions

Faqs on GLP-1 maintenance

There is no fixed time limit. We decide together based on:

  • Your weight trend
  • Appetite control
  • Side effects
  • Life plans, for example pregnancy

For your weight trend aim for stable within plus or minus 2kg over 8 to 12 weeks. If you are steady and comfortable, stay on the lowest effective dose with reviews every 8 to 12 weeks.

If your BMI is below 25, avoid increasing the dose unless your clinician records a clear reason. NHS use of Wegovy is usually up to 2 years in specialist services. Private care can differ but still follows a safety-first approach.

Look for clear signals over 4 to 8 weeks:

  • Good: Your hunger is mostly calm, meals feel manageable, weight is stable.
  • Good: Side effects are less visible than at a dose of 2.4mg.
  • Watch-outs: Food noise returns, evening grazing, or a gain of more than 2 to 3 kg.

If watch-outs show up, we may try 2.4mg and review in 4 to 8 weeks. If there is no clear benefit or side effects rise, we step back to 1.7mg.

The fear is common among patients. We reduce by one step only and set a safety net before you start:

  • Your ‘regain trigger,’ for example a gain of 2 to 3kg in 4 to 8 weeks, waist up by 3cm, or hunger most days
  • A pre-booked review at 8 weeks

If the trigger is hit, you can step back up one dose and message us. Early action beats months of drift.

Sometimes, yes, but only with a plan:

  • Slow dose reductions (one step every 4 weeks when stable)
  • Protein target 1.2 to 1.6g per kg per day
  • Two short strength sessions each week to protect muscle

Evidence for tapering is limited, so we monitor closely. If your hunger or weight starts to drift, we pause or step back up. Planning pregnancy?

Stop at least 2 months before trying if on Semaglutide, or at least 1 month if on Tirzepatide.

For Wegovy, NHS services currently allow up to 2 years in eligible patients. Outside the NHS, duration depends on clinical benefit, tolerability and your goals, with reviews every 8 to 12 weeks. In all settings we use the lowest effective dose and put safety first.

Possibly, and sometimes it is the right move, for example due to side effects, supply, or limited progress. Any switch needs:

  • A clinician-led plan
  • No overlapping injections
  • A short period on the new medicine to find the right dose
  • Checks on contraception and pregnancy timing
  • A review in 4 to 8 weeks to confirm stability

Useful links

NHS medicine information

NICE clinical guidelines

Professional certifications

Key clinical trial programmes

James Reynolds - MPharm, DipClinPh, PgCert Derm, SCOPE, IP. Lead Clinical Pharmacist, Lotus Weight Loss Clinic Medically reviewed
—James Reynolds

Last reviewed: September 30, 2025

James Reynolds – MPharm, DipClinPh, PgCert Derm, SCOPE, IP

Lead Clinical Pharmacist, Lotus Weight Loss Clinic

James is a UK-registered pharmacist with over 15 years’ experience in NHS and private healthcare. He specialises in weight management and GLP-1 prescribing, and holds SCOPE certification in obesity care — a globally recognised standard for evidence-based treatment. More about James

Login to reorder..

To have an account you must first purchase a medication.