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Wegovy (Semaglutide) maintenance advice

Wegovy maintenance

Keep your results on the lowest Wegovy dose that works for you

Written by: James Reynolds – MPharm, DipClinPh, PgCert Derm, SCOPE, IP

You’ve put in the effort to get here. Wegovy maintenance dosing means keeping it off without upending your life. This page explains the dose you’re likely to stay on, what to do if hunger or weight creep back up, how to handle travel and busy weeks, and when it’s best to speak to someone at Lotus Weight Loss.

Aims of maintenance: Stay on the lowest weekly dose that keeps your weight steady and your appetite quiet, with side‑effects you can live with. We’ll review regularly and adjust if life changes.

At-a-glance Wegovy maintenance rules

  • Maintenance dose: Typical maintenance dose is usually 1.7mg or 2.4mg weekly, however you can choose to remain on a lower dose than this (0.25mg, 0.5mg or 1mg) if you find this is what works best for you..
  • Missed dose: If you’re 5 days or less late, take the dose now; if it’s more than 5 days late, skip it and take your next dose on your usual day. Never take two doses together.
  • Changing pen day: You’ll need to leave at least 3 full days between doses, then stick to the new weekly day.
  • Safe storage: Once in use, keep the pen below 30 °C for up to 28 days between 8-30 °C or refrigerated at 2-8 °C. Never freeze.
  • Pregnancy & breastfeeding: Do not use. Stop using at least 2 months before trying to conceive. If pregnancy occurs, stop and contact the clinic.
  • Switching treatments: Do not overlap with any other GLP‑1/GIP or GLP‑1 medicine unless specifically prescribed.

Not sure what to do? Message the clinic and let a prescriber help.

Wegovy maintenance dosing table

The typical Wegovy maintenance doses are 1.7mg or 2.4mg weekly, however you can choose to remain on a lower dose than this (0.25mg, 0.5mg or 1mg) if you find this is what works best for you. Use this table as a guide.

Weekly doseWhen we useWhat to watchNext step
1.7 mg You feel ok. Hunger mostly quiet.Returning hunger, grazing, or 2-3kg up in 4-8 weeks.If needed, step up to 2.4mg, review in 4-8 weeks.
2.4 mg1.7mg was not enough.More nausea / constipation for some.If well‑controlled 8-12 weeks but side‑effects annoy, trial 1.7mg.
Wegovy maintenance dose can be lower (0.25mg, 0.5mg or 1mg) if that’s what works for you.

Note: At lower BMIs we keep a light touch. We won’t increase dose below a healthy BMI unless there’s a clear clinical reason we agree together.

When you notice a creep

Look at your weight trends, not just a single weigh‑in. If you’re 2-3kg up across a month or two, or clothes tighten and hunger feels loud most days, treat that as your early warning.

A simple seven‑day reset

For one week, do the basics well. Eat three meals. Add a palm of protein each time. Go heavier on veg and fibre. Keep water close. Add 2,000 steps above your usual routine. Keep a steady bedtime. On day eight, take stock. If your weight is still climbing message the clinic and we’ll adjust your plan together.

Protecting your results

Maintenance rests on a few easy wins.

Those being:

  • Protein on each plate.
  • Veg or salad most meals.
  • Realistic carbs around activity so you’re fuelled not flat.
  • A step target you can hit most days.
  • Consistent bedtime and good sleep.

Small, boring habits do most of the heavy lifting during Wegovy maintenance. Medication supports them; it doesn’t replace them. If you’re peri‑ or post‑menopausal, or your cycle shifts appetite, tell us so we can pace reviews and targets accordingly.

Real life: travel, celebrations, busy weeks

Travel

Keep pens in hand luggage. If the pen is in use you can keep it at room temperature below 30 °C. In hot weather use a small medication cooler.

Big meals & occasions

Don’t arrive starving. Eat normally through the day. Start with protein and veg, enjoy what you fancy, and move on. The next day, return to normal. No ‘punishment’ routines.

Stressful weeks

Set two easy wins: a simple breakfast (e.g., yoghurt with berries and oats, or eggs on toast) and a 10‑minute walk after lunch. Tiny habits will keep you steady.

Alcohol

Eat first, set a limit upfront, and alternate with water. The goal isn’t perfection; it’s staying in charge.

Common problems on Wegovy maintenance

  • Nausea: Smaller, slower meals. Go easy on greasy food. Sip still drinks. Ginger or peppermint often helps. If it keeps happening, tell us.
  • Constipation: Fluids, fibre (veg, oats, beans, psyllium); gentle movement most days. If needed, speak to a pharmacist about an over‑the‑counter options.
  • Reflux: Lighter portions, avoid late heavy meals and keep alcohol modest. If it’s frequent, we’ll review.
  • Low energy: Check the basics such as enough protein, enough carbs around activity, and a sensible bedtime. If that doesn’t shift it, get in touch.
  • Red flags: Severe tummy pain (especially central), ongoing vomiting, dehydration, black stools, fainting, or anything that just feels wrong. Use urgent care NHS111 or contact us.

Medicines and other treatments

Wegovy maintenance can slow stomach emptying. Most everyday medicines are fine, but if you take medicines that need tight monitoring such as warfarin tell your prescriber so they can keep an eye on levels or INR as usual. Do not change doses of any medicines without advice.

Combined hormonal contraception generally still works; if vomiting or severe diarrhoea happens soon after a pill, follow your brand’s missed‑pill instructions or speak to a pharmacist. Always tell any new clinician you’re using a GLP‑1 medicine so they can tailor advice.

NHS and private care in the UK

On the NHS, Wegovy is used within specialist services under set criteria and time‑limited pathways. In private care, we follow the same safety evidence and review you regularly, with clear goals and adjustments based on clinical need and how you’re feeling. Either way, the plan is safe, monitored and tailored to your life.

If you’re thinking about stopping

Many people regain some weight after stopping Wegovy maintenance. That’s biology, not failure. If you plan a break, keep the easy habits such as protein, fibre, steps and sleep. Book a follow‑up in 4-8 weeks. If weight starts to climb and keeps going, we can talk about restarting or other options.

What to track once a week

  • One weigh‑in, same day and time
  • A quick hunger score out of ten
  • Your 7‑day step average
  • A short note on sleep and anything that explains the week (periods, travel, illness, celebrations, new medicines)

When to act: If hunger is 6+ most days for two weeks, or your weight trend rises for four weeks, tighten the basics for a week. If it doesn’t settle, contact the clinic to review your plan or dose.

Common questions

Faqs on Wegovy maintenance

Not necessarily. Wegovy maintenance isn’t a life sentence; it’s a period of keeping results steady on the lightest touch that works. Some people taper down over time as habits bed in; others need longer support. We’ll review and adapt if life changes.

Check the basics for a fortnight. Check protein at meals, sleep, steps and alcohol. If hunger stays loud or weight creeps up despite doing the basics, contact the clinic. We’ll look for triggers (stress, medicines, cycle) and decide whether to persist, step down briefly to settle side‑effects, or explore alternatives.

You can, but pace yourself. Alcohol lowers food judgement and can irritate reflux. Eat first, set a limit up front, and alternate with water. If you notice snacky evenings after drinking, plan a protein‑rich meal before you go out and keep simple options at home so you don’t end the night in the biscuit tin.

No. We don’t escalate dose below a healthy BMI unless there’s a clear clinical reason we agree together. The aim of Wegovy maintenance is the lowest effective dose that keeps you well. If side‑effects grow or appetite is quiet, we’ll consider holding or stepping down and see how you feel over the next 8-12 weeks.

James Reynolds - MPharm, DipClinPh, PgCert Derm, SCOPE, IP. Lead Clinical Pharmacist, Lotus Weight Loss Clinic Medically reviewed
—James Reynolds

Last reviewed: September 30, 2025

James Reynolds – MPharm, DipClinPh, PgCert Derm, SCOPE, IP

Lead Clinical Pharmacist, Lotus Weight Loss Clinic

James is a UK-registered pharmacist with over 15 years’ experience in NHS and private healthcare. He specialises in weight management and GLP-1 prescribing, and holds SCOPE certification in obesity care — a globally recognised standard for evidence-based treatment. More about James

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