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Wegovy and women’s health: what to consider before starting




Written by:
<br:


James Reynolds
MPharm | SCOPE


Lead Pharmacist</br:

"Considering Wegovy for weight loss? Women’s health factors play a crucial role in deciding if this medication is right for you. From reproductive health considerations to understanding potential side effects, this guide covers what women need to know before starting Wegovy."
Confident woman who had successful weight loss with Wegovy.

💡Key takeaways 

1️⃣ Wegovy offers substantial weight loss benefits, particularly for women with obesity or obesity-related health conditions.

2️⃣ Reproductive health is a significant factor, as Wegovy is contraindicated during pregnancy.

3️⃣ Eligibility criteria in the UK vary, and Wegovy is typically prescribed for managing obesity, not cosmetic weight loss.

4️⃣ Potential side effects include gastrointestinal issues, which may impact women differently than men.

5️⃣ Lifestyle adjustments improve outcomes, combining Wegovy with diet and exercise enhances weight loss success.

Wegovy and women’s health: understanding the basics

Wegovy (semaglutide) is gaining attention as a groundbreaking medication for weight management. It belongs to a class of drugs known as GLP-1 receptor agonists, which work by mimicking the hormone glucagon-like peptide-1 to regulate appetite and glucose metabolism. Initially developed to manage type 2 diabetes, Wegovy is now widely prescribed for weight loss, particularly among women dealing with obesity or related health conditions.

Why Women Should Consider Wegovy for Weight Loss

Clinical trials have shown that Wegovy can result in significant weight reduction. In a pivotal placebo-controlled study, participants experienced an average weight loss of 12.4% over 68 weeks. Notably, women made up 74% of the study group, indicating the medication’s particular relevance to female patients. Furthermore, research indicates that women, especially those over 55 or with cardiovascular conditions, may experience even greater benefits compared to men.

For women, obesity often comes with heightened health risks, including heart disease, type 2 diabetes, and polycystic ovary syndrome (PCOS). Wegovy not only aids in shedding pounds but also positively impacts cardiovascular health. According to the Journal of the American College of Cardiology, women with obesity and heart failure who used Wegovy saw a more significant reduction in weight compared to their male counterparts (9.6% vs. 7.2%).

Women contemplating Wegovy should weigh its benefits against potential risks, especially regarding reproductive health. This medication is contraindicated during pregnancy and should be discontinued at least two months prior to conception. Since obesity can affect menstrual cycles and fertility, discussing the potential impacts of Wegovy with a healthcare provider is crucial.

To explore other weight loss treatments and medications, visit our Treatments page.

Health considerations and safety: what women need to know

While Wegovy’s weight loss potential is promising, it’s essential to understand the health considerations specific to women.

Reproductive Health and Wegovy

One of the most significant concerns is the impact on reproductive health. Wegovy is strictly contraindicated during pregnancy, as animal studies have shown potential harm to the fetus, including skeletal and visceral malformations. Due to its long half-life, women planning to conceive should stop Wegovy at least two months before attempting pregnancy. Additionally, it is not recommended during breastfeeding.

Menstrual Cycle and Fertility:

Some studies suggest that semaglutide, the active ingredient in Wegovy, may affect ovarian function. Animal research indicates it may alter the estrus cycle length and reduce corpora lutea formation, potentially impacting fertility. Women of childbearing age should discuss these risks with their healthcare provider before beginning treatment.

Managing Side Effects

Wegovy’s most common side effects include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. These effects can be mitigated by gradually increasing the dose over a 16–20 week period. In rare cases, Wegovy can cause pancreatitis or severe allergic reactions, including anaphylaxis. Women with a history of pancreatitis should not use Wegovy.

Want to know more about Wegovy pricing and availability? Check our Medications and Pricing page.

Maximizing Wegovy’s benefits: practical tips for women

Woman balancing healthy eating and physical activity while using Wegovy.

For women aiming to achieve sustainable weight loss with Wegovy, integrating lifestyle changes is crucial.

Diet and Nutrition

Adopting a balanced, reduced-calorie diet significantly enhances the effectiveness of Wegovy. Incorporating whole grains, lean proteins, and plenty of vegetables not only aids weight loss but also supports overall health.

Physical Activity

Women who combine Wegovy with regular exercise, such as strength training and cardio, typically see better results. Aiming for at least 150 minutes of moderate activity per week is recommended.

Behavioral Strategies
A visual image of ways to enhance Wegovy outcomes with support.

Women over 55, in particular, have shown improved outcomes when Wegovy is paired with behavioral support like counseling, progress tracking, or group sessions. Consider joining a support group or using a weight loss tracking app to stay motivated.

Considering starting Wegovy? Visit our Thinking of Starting? page for guidance.

Conclusion

Wegovy can be a powerful tool for women struggling with weight management, particularly those facing obesity-related health issues. However, it’s vital to weigh the benefits against potential reproductive health concerns and manage side effects responsibly. By incorporating dietary changes, physical activity, and behavioral support, women can maximize the positive effects of Wegovy and improve long-term outcomes.

Frequently Asked Questions

Can I take Wegovy if I’m planning to get pregnant?

No, Wegovy is contraindicated during pregnancy due to potential fetal harm. Discontinue the medication at least two months before attempting conception.

What are the common side effects of Wegovy?

Gastrointestinal issues such as nausea and vomiting are common. Gradual dose escalation can help reduce these symptoms.

Is Wegovy suitable for women over 55?

Yes, studies show women over 55 may experience greater weight loss with Wegovy, especially when combined with lifestyle interventions.

How can I minimize side effects?

Starting with a lower dose and gradually increasing it helps manage gastrointestinal symptoms. Consult your healthcare provider for a tailored dosing plan.

What lifestyle changes should I make while on Wegovy?

Focus on a balanced diet, regular physical activity, and behavioral strategies such as progress tracking and group support to maximize results.

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